Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ACHE	HGNC:108 (HGNC) 43 (Entrez Gene) 100740 (OMIM) ACHE (Alliance of Genome Resources)	Chr7 q22.1	Chr7:100889994-100896994 (-) GRCh38	Alzheimer's disease cannabis dependence drug dependence epilepsy heroin dependence myasthenia gravis subacute delirium	P22303 (UniProt | EBI) NM_015831 (RefSeq)
mouse	Ache	MGI:87876 (MGI) 11423 (Entrez Gene) Gene Tree Ache (Alliance of Genome Resources)	Chr5 76.32 cM	Chr5:137286516-137292728 (+) GRCm39		11423 (NCBI Gene Model) P21836 (UniProt | EBI) NM_001290010 (RefSeq)
rat	Ache	RGD:69313 (Rat Genome Database) 83817 (Entrez Gene) Ache (Alliance of Genome Resources)	Chr12			P37136 (UniProt | EBI) NM_172009 (RefSeq)
zebrafish	ache	ZDB-GENE-010906-1 (Zebrafish Model Organism Database) 114549 (Entrez Gene) ache (Alliance of Genome Resources)	Chr7			Q9DDE3 (UniProt | EBI) NM_131846 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.