Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	AGER	HGNC:320 (HGNC) 177 (Entrez Gene) 600214 (OMIM) AGER (Alliance of Genome Resources)	Chr6 p21.32	Chr6:32180968-32184322 (-) GRCh38	acute kidney failure Alzheimer's disease aspergillosis cardiovascular system disease chronic kidney disease coronary artery disease cystic fibrosis diabetic retinopathy lupus nephritis melanoma mild cognitive impairment morbid obesity multiple sclerosis myocardial infarction proteinuria psoriasis schizophrenia schizotypal personality disorder systemic lupus erythematosus type 1 diabetes mellitus type 2 diabetes mellitus vascular skin disease	Q15109 (UniProt | EBI) NM_001206966 (RefSeq)
mouse	Ager	MGI:893592 (MGI) 11596 (Entrez Gene) Gene Tree Ager (Alliance of Genome Resources)	Chr17 18.18 cM	Chr17:34816836-34819910 (+) GRCm39		ENSMUSG00000015452 (Ensembl Gene Model) ENSMUSP00000015596 (Ensembl) ENSMUST00000015596 (Ensembl)
rat	Ager	RGD:69258 (Rat Genome Database) 81722 (Entrez Gene) Ager (Alliance of Genome Resources)	Chr20 p12			Q63495 (UniProt | EBI) NM_053336 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.