Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	APOC3	HGNC:610 (HGNC) 345 (Entrez Gene) 107720 (OMIM) APOC3 (Alliance of Genome Resources)	Chr11 q23.3	Chr11:116829706-116833072 (+) GRCh38	apolipoprotein C-III deficiency chronic kidney disease cognitive disorder coronary artery disease familial combined hyperlipidemia glucose intolerance hepatocellular carcinoma hyperlipoproteinemia type III type 1 diabetes mellitus	P02656 (UniProt | EBI) NM_000040 (RefSeq)
mouse	Apoc3	MGI:88055 (MGI) 11814 (Entrez Gene) Gene Tree Apoc3 (Alliance of Genome Resources)	Chr9 25.36 cM	Chr9:46144348-46146934 (-) GRCm39		11814 (NCBI Gene Model) P33622 (UniProt | EBI) NM_001289755 (RefSeq)
rat	Apoc3	RGD:2136 (Rat Genome Database) 24207 (Entrez Gene) Apoc3 (Alliance of Genome Resources)	Chr8 q22			P06759 (UniProt | EBI) NM_012501 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.