Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	LGR5	HGNC:4504 (HGNC) 8549 (Entrez Gene) 606667 (OMIM) LGR5 (Alliance of Genome Resources)	Chr12 q21.1	Chr12:71439129-71586310 (+) GRCh38		O75473 (UniProt | EBI) NM_001277226 (RefSeq)
mouse	Lgr5	MGI:1341817 (MGI) 14160 (Entrez Gene) Gene Tree Lgr5 (Alliance of Genome Resources)	Chr10 63.51 cM	Chr10:115286219-115423685 (-) GRCm39	ankyloglossia	14160 (NCBI Gene Model) Q9Z1P4 (UniProt | EBI) NM_010195 (RefSeq)
rat	Lgr5	RGD:1307733 (Rat Genome Database) 299802 (Entrez Gene) Lgr5 (Alliance of Genome Resources)	Chr7 q22			D4AC13 (UniProt | EBI) NM_001106784 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.