Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ERCC8	HGNC:3439 (HGNC) 1161 (Entrez Gene) 609412 (OMIM) ERCC8 (Alliance of Genome Resources)	Chr5 q12.1	Chr5:60866454-60945073 (-) GRCh38	Cockayne syndrome Cockayne syndrome A UV-sensitive syndrome	Q13216 (UniProt | EBI) NM_001290285 (RefSeq)
mouse	Ercc8	MGI:1919241 (MGI) 71991 (Entrez Gene) Gene Tree Ercc8 (Alliance of Genome Resources)	Chr13 59.69 cM	Chr13:108295265-108331898 (+) GRCm39	Cockayne syndrome	ENSMUSG00000021694 (Ensembl Gene Model) ENSMUSP00000059211 (Ensembl) ENSMUST00000054835 (Ensembl)
rat	Ercc8	RGD:1311570 (Rat Genome Database) 310071 (Entrez Gene) Ercc8 (Alliance of Genome Resources)	Chr2 q14			NP_001101120 (RefSeq) NM_001107650 (RefSeq)
zebrafish	ercc8	ZDB-GENE-041010-60 (Zebrafish Model Organism Database) 449811 (Entrez Gene) ercc8 (Alliance of Genome Resources)	Chr8			NP_001005984 (RefSeq) NM_001005984 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.