Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	EIF4G1	HGNC:3296 (HGNC) 1981 (Entrez Gene) 600495 (OMIM) EIF4G1 (Alliance of Genome Resources)	Chr3 q27.1	Chr3:184314495-184335358 (+) GRCh38	late onset Parkinson's disease	Q04637 (UniProt | EBI) NM_182917 (RefSeq)
mouse	Eif4g1	MGI:2384784 (MGI) 208643 (Entrez Gene) Gene Tree Eif4g1 (Alliance of Genome Resources)	Chr16 12.49 cM	Chr16:20491457-20511633 (+) GRCm39		208643 (NCBI Gene Model) Q6NZJ6 (UniProt | EBI) NM_001403460 (RefSeq)
rat	Eif4g1	RGD:1306144 (Rat Genome Database) 287986 (Entrez Gene) Eif4g1 (Alliance of Genome Resources)	Chr11 q23			NP_001414405 (RefSeq) NM_001427476 (RefSeq)
zebrafish	eif4g1a	ZDB-GENE-070112-702 (Zebrafish Model Organism Database) 572435 (Entrez Gene) eif4g1a (Alliance of Genome Resources)	Chr2			NP_001073669 (RefSeq) NM_001080200 (RefSeq)
	eif4g1b	ZDB-GENE-140605-1 (Zebrafish Model Organism Database) 100333590 (Entrez Gene) eif4g1b (Alliance of Genome Resources)	ChrUN			XP_068073817 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.