Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SLC25A4	HGNC:10990 (HGNC) 291 (Entrez Gene) 103220 (OMIM) SLC25A4 (Alliance of Genome Resources)	Chr4 q35.1	Chr4:185143266-185150382 (+) GRCh38	autosomal dominant progressive external ophthalmoplegia with mitochondrial DNA deletions 2 chronic progressive external ophthalmoplegia dilated cardiomyopathy 1H hypertrophic cardiomyopathy mitochondrial DNA depletion syndrome 12a mitochondrial DNA depletion syndrome 12b mitochondrial myopathy	P12235 (UniProt | EBI) NM_001151 (RefSeq)
mouse	Slc25a4	MGI:1353495 (MGI) 11739 (Entrez Gene) Gene Tree Slc25a4 (Alliance of Genome Resources)	Chr8 26.22 cM	Chr8:46660205-46664099 (-) GRCm39		11739 (NCBI Gene Model) P48962 (UniProt | EBI) NM_007450 (RefSeq)
rat	Slc25a4	RGD:620352 (Rat Genome Database) 85333 (Entrez Gene) Slc25a4 (Alliance of Genome Resources)	Chr16 q11			Q05962 (UniProt | EBI) NM_053515 (RefSeq)
zebrafish	slc25a4	ZDB-GENE-030131-5275 (Zebrafish Model Organism Database) 327067 (Entrez Gene) slc25a4 (Alliance of Genome Resources)	Chr1			NP_999867 (RefSeq) NM_214702 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.