Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	SETD2	HGNC:18420 (HGNC) 29072 (Entrez Gene) 612778 (OMIM) SETD2 (Alliance of Genome Resources)	Chr3 p21.31	Chr3:47016428-47164840 (-) GRCh38	autosomal dominant intellectual developmental disorder clear cell renal cell carcinoma colorectal cancer gastrointestinal stromal tumor idiopathic pulmonary fibrosis lung adenocarcinoma malignant mesothelioma malignant pleural mesothelioma	Q9BYW2 (UniProt | EBI) NM_012271 (RefSeq)
mouse	Setd2	MGI:1918177 (MGI) 235626 (Entrez Gene) Gene Tree Setd2 (Alliance of Genome Resources)	Chr9 60.0 cM	Chr9:110361665-110447701 (+) GRCm39		ENSMUSG00000044791 (Ensembl Gene Model) ENSMUSP00000116313 (Ensembl) ENSMUST00000153838 (Ensembl)
rat	Setd2	RGD:1305576 (Rat Genome Database) 316013 (Entrez Gene) Setd2 (Alliance of Genome Resources)	Chr8 q32			NP_001388092 (RefSeq) NM_001401163 (RefSeq)
zebrafish	setd2	ZDB-GENE-030131-2140 (Zebrafish Model Organism Database) 794199 (Entrez Gene) setd2 (Alliance of Genome Resources)	Chr16			XP_009290459 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.