Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PFKFB4	HGNC:8875 (HGNC) 5210 (Entrez Gene) 605320 (OMIM) PFKFB4 (Alliance of Genome Resources)	Chr3 p21.31	Chr3:48517684-48563136 (-) GRCh38		Q16877 (UniProt | EBI) NM_001317138 (RefSeq)
mouse	Pfkfb4	MGI:2687284 (MGI) 270198 (Entrez Gene) Gene Tree Pfkfb4 (Alliance of Genome Resources)	Chr9 59.63 cM	Chr9:108820846-108861296 (+) GRCm39		ENSMUSG00000025648 (Ensembl Gene Model) ENSMUSP00000142378 (Ensembl) ENSMUST00000198140 (Ensembl)
rat	Pfkfb4	RGD:3310 (Rat Genome Database) 54283 (Entrez Gene) Pfkfb4 (Alliance of Genome Resources)	Chr8 q32			P25114 (UniProt | EBI) NM_001431583 (RefSeq)
zebrafish	pfkfb4a	ZDB-GENE-051120-51 (Zebrafish Model Organism Database) 556190 (Entrez Gene) pfkfb4a (Alliance of Genome Resources)	Chr11			NP_001032454 (RefSeq) NM_001037377 (RefSeq)
	pfkfb4b	ZDB-GENE-031031-4 (Zebrafish Model Organism Database) 386663 (Entrez Gene) pfkfb4b (Alliance of Genome Resources)	Chr6			NP_942111 (RefSeq) NM_198816 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.