Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PDE4C	HGNC:8782 (HGNC) 5143 (Entrez Gene) 600128 (OMIM) PDE4C (Alliance of Genome Resources)	Chr19 p13.11	Chr19:18207961-18255419 (-) GRCh38		Q08493 (UniProt | EBI) NM_001369701 (RefSeq)
mouse	Pde4c	MGI:99556 (MGI) 110385 (Entrez Gene) Gene Tree Pde4c (Alliance of Genome Resources)	Chr8 34.15 cM	Chr8:71176485-71203835 (+) GRCm39		110385 (NCBI Gene Model) Q3UEI1 (UniProt | EBI) NM_001310465 (RefSeq)
rat	Pde4c	RGD:727918 (Rat Genome Database) 290646 (Entrez Gene) Pde4c (Alliance of Genome Resources)	Chr16 p14			P14644 (UniProt | EBI) NM_001276765 (RefSeq)
zebrafish	pde4ca	ZDB-GENE-070912-373 (Zebrafish Model Organism Database) 565259 (Entrez Gene) pde4ca (Alliance of Genome Resources)	Chr2			XP_021326921 (RefSeq)
	pde4cb	ZDB-GENE-030131-4075 (Zebrafish Model Organism Database) 571344 (Entrez Gene) pde4cb (Alliance of Genome Resources)	Chr11			XP_021335381 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.