Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	NLGN4X	HGNC:14287 (HGNC) 57502 (Entrez Gene) 300427 (OMIM) NLGN4X (Alliance of Genome Resources)	ChrX p22.32-p22.31	ChrX:5840637-6228867 (-) GRCh38	autistic disorder	Q8N0W4 (UniProt | EBI) NM_020742 (RefSeq)
	NLGN4Y	HGNC:15529 (HGNC) 22829 (Entrez Gene) 400028 (OMIM) NLGN4Y (Alliance of Genome Resources)	ChrY q11.221	ChrY:14522573-14845654 (+) GRCh38		Q8NFZ3 (UniProt | EBI) NM_001365586 (RefSeq)
mouse	Nlgn4l	MGI:3775191 (MGI) 100113365 (Entrez Gene) Gene Tree Nlgn4l (Alliance of Genome Resources)	ChrXY Syntenic	ChrX:169067543-169089017 (-) GRCm39	autism spectrum disorder	ENSMUSG00000121607 (Ensembl Gene Model) ENSMUSP00000159847 (Ensembl) ENSMUST00000249668 (Ensembl)
zebrafish	nlgn4xb	ZDB-GENE-100309-1 (Zebrafish Model Organism Database) 100147967 (Entrez Gene) nlgn4xb (Alliance of Genome Resources)	Chr9			NP_001159809 (RefSeq) NM_001166337 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.