Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ACVR1	HGNC:171 (HGNC) 90 (Entrez Gene) 102576 (OMIM) ACVR1 (Alliance of Genome Resources)	Chr2 q24.1	Chr2:157736251-157876330 (-) GRCh38	exfoliation syndrome fibrodysplasia ossificans progressiva primary angle-closure glaucoma primary open angle glaucoma	Q04771 (UniProt | EBI) NM_001347665 (RefSeq)
mouse	Acvr1	MGI:87911 (MGI) 11477 (Entrez Gene) Gene Tree Acvr1 (Alliance of Genome Resources)	Chr2 33.05 cM	Chr2:58336450-58456840 (-) GRCm39	fibrodysplasia ossificans progressiva	11477 (NCBI Gene Model) P37172 (UniProt | EBI) NM_001110204 (RefSeq)
rat	Acvr1	RGD:620200 (Rat Genome Database) 79558 (Entrez Gene) Acvr1 (Alliance of Genome Resources)	Chr3 q21			P80201 (UniProt | EBI) NM_001431445 (RefSeq)
zebrafish	acvr1l	ZDB-GENE-990415-9 (Zebrafish Model Organism Database) 30615 (Entrez Gene) acvr1l (Alliance of Genome Resources)	Chr2			NP_571420 (RefSeq) NM_131345 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.