Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	DRD2	HGNC:3023 (HGNC) 1813 (Entrez Gene) 126450 (OMIM) DRD2 (Alliance of Genome Resources)	Chr11 q23.2	Chr11:113409605-113475691 (-) GRCh38	alcohol dependence alcohol-induced mental disorder anxiety disorder cocaine dependence depressive disorder end stage renal disease heroin dependence hypertension migraine with aura movement disease nicotine dependence obesity opiate dependence type 2 diabetes mellitus	P14416 (UniProt | EBI) NM_000795 (RefSeq)
mouse	Drd2	MGI:94924 (MGI) 13489 (Entrez Gene) Gene Tree Drd2 (Alliance of Genome Resources)	Chr9 26.72 cM	Chr9:49251927-49319477 (+) GRCm39	Parkinson's disease primary hyperaldosteronism	ENSMUSG00000032259 (Ensembl Gene Model) ENSMUSP00000075170 (Ensembl) ENSMUST00000075764 (Ensembl)
rat	Drd2	RGD:2520 (Rat Genome Database) 24318 (Entrez Gene) Drd2 (Alliance of Genome Resources)	Chr8 q23			P61169 (UniProt | EBI) NM_012547 (RefSeq)
zebrafish	drd2a	ZDB-GENE-021119-2 (Zebrafish Model Organism Database) 282557 (Entrez Gene) drd2a (Alliance of Genome Resources)	Chr15			NP_898891 (RefSeq) NM_183068 (RefSeq)
	drd2b	ZDB-GENE-030910-2 (Zebrafish Model Organism Database) 378719 (Entrez Gene) drd2b (Alliance of Genome Resources)	Chr5			NP_922918 (RefSeq) NM_197936 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.