Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	RPL5	HGNC:10360 (HGNC) 6125 (Entrez Gene) 603634 (OMIM) RPL5 (Alliance of Genome Resources)	Chr1 p22.1	Chr1:92831986-92841924 (+) GRCh38	Diamond-Blackfan anemia 6 glioblastoma T-cell acute lymphoblastic leukemia	P46777 (UniProt | EBI) NM_000969 (RefSeq)
mouse	Rpl5	MGI:102854 (MGI) 100503670 (Entrez Gene) Gene Tree Rpl5 (Alliance of Genome Resources)	Chr5 Syntenic	Chr5:108048388-108056871 (+) GRCm39	Diamond-Blackfan anemia 6	100503670 (NCBI Gene Model) P47962 (UniProt | EBI) NM_016980 (RefSeq)
rat	Rpl5	RGD:619825 (Rat Genome Database) 81763 (Entrez Gene) Rpl5 (Alliance of Genome Resources)	Chr14 p22			P09895 (UniProt | EBI) NM_031099 (RefSeq)
zebrafish	rpl5a	ZDB-GENE-030131-5161 (Zebrafish Model Organism Database) 326961 (Entrez Gene) rpl5a (Alliance of Genome Resources)	Chr2			NP_956050 (RefSeq) NM_199756 (RefSeq)
	rpl5b	ZDB-GENE-040625-93 (Zebrafish Model Organism Database) 415196 (Entrez Gene) rpl5b (Alliance of Genome Resources)	Chr6			NP_001002106 (RefSeq) NM_001002106 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.