Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ADRB1	HGNC:285 (HGNC) 153 (Entrez Gene) 109630 (OMIM) ADRB1 (Alliance of Genome Resources)	Chr10 q25.3	Chr10:114043866-114046904 (+) GRCh38	chronic obstructive pulmonary disease congestive heart failure hypertension low tension glaucoma nephrosclerosis obstructive sleep apnea periodontitis	P08588 (UniProt | EBI) NM_000684 (RefSeq)
mouse	Adrb1	MGI:87937 (MGI) 11554 (Entrez Gene) Gene Tree Adrb1 (Alliance of Genome Resources)	Chr19 51.96 cM	Chr19:56710549-56713582 (+) GRCm39		11554 (NCBI Gene Model) P34971 (UniProt | EBI) NM_007419 (RefSeq)
rat	Adrb1	RGD:2059 (Rat Genome Database) 24925 (Entrez Gene) Adrb1 (Alliance of Genome Resources)	Chr1 q55			P18090 (UniProt | EBI) NM_012701 (RefSeq)
zebrafish	adrb1	ZDB-GENE-081022-145 (Zebrafish Model Organism Database) 557194 (Entrez Gene) adrb1 (Alliance of Genome Resources)	Chr12			NP_001122161 (RefSeq) NM_001128689 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.