Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CHKB	HGNC:1938 (HGNC) 1120 (Entrez Gene) 612395 (OMIM) CHKB (Alliance of Genome Resources)	Chr22 q13.33	Chr22:50578959-50601455 (-) GRCh38	intellectual disability megaconial type congenital muscular dystrophy muscular dystrophy narcolepsy recurrent hypersomnia	Q9Y259 (UniProt | EBI) NM_152253 (RefSeq)
mouse	Chkb	MGI:1328313 (MGI) 12651 (Entrez Gene) Gene Tree Chkb (Alliance of Genome Resources)	Chr15 44.89 cM	Chr15:89310563-89314111 (-) GRCm39	megaconial type congenital muscular dystrophy	ENSMUSG00000022617 (Ensembl Gene Model) ENSMUSP00000023289 (Ensembl) ENSMUST00000023289 (Ensembl)
rat	Chkb	RGD:61826 (Rat Genome Database) 29367 (Entrez Gene) Chkb (Alliance of Genome Resources)	Chr7 q34			O54783 (UniProt | EBI) NM_017177 (RefSeq)
zebrafish	chkb	ZDB-GENE-030131-2928 (Zebrafish Model Organism Database) 563589 (Entrez Gene) chkb (Alliance of Genome Resources)	Chr18			NP_001093482 (RefSeq) NM_001100012 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.