Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TLR5	HGNC:11851 (HGNC) 7100 (Entrez Gene) 603031 (OMIM) TLR5 (Alliance of Genome Resources)	Chr1 q41	Chr1:223109404-223143292 (-) GRCh38	cystic fibrosis cystitis Legionnaires' disease melioidosis systemic lupus erythematosus	O60602 (UniProt | EBI) NM_003268 (RefSeq)
mouse	Tlr5	MGI:1858171 (MGI) 53791 (Entrez Gene) Gene Tree Tlr5 (Alliance of Genome Resources)	Chr1 86.12 cM	Chr1:182782353-182804010 (+) GRCm39		ENSMUSG00000079164 (Ensembl Gene Model) ENSMUSP00000141318 (Ensembl) ENSMUST00000193687 (Ensembl)
rat	Tlr5	RGD:631351 (Rat Genome Database) 289337 (Entrez Gene) Tlr5 (Alliance of Genome Resources)	Chr13 q26			NP_001139300 (RefSeq) NM_001145828 (RefSeq)
zebrafish	tlr5a	ZDB-GENE-040219-14 (Zebrafish Model Organism Database) 403138 (Entrez Gene) tlr5a (Alliance of Genome Resources)	Chr20			XP_001919052 (RefSeq)
	tlr5b	ZDB-GENE-040219-15 (Zebrafish Model Organism Database) 403139 (Entrez Gene) tlr5b (Alliance of Genome Resources)	Chr20			NP_001124067 (RefSeq) NM_001130595 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.