Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	MAP3K5	HGNC:6857 (HGNC) 4217 (Entrez Gene) 602448 (OMIM) MAP3K5 (Alliance of Genome Resources)	Chr6 q23.3	Chr6:136557046-136793097 (-) GRCh38	Huntington's disease	Q99683 (UniProt | EBI) NM_005923 (RefSeq)
mouse	Map3k5	MGI:1346876 (MGI) 26408 (Entrez Gene) Gene Tree Map3k5 (Alliance of Genome Resources)	Chr10 9.35 cM	Chr10:19810218-20018499 (+) GRCm39		ENSMUSG00000071369 (Ensembl Gene Model) ENSMUSP00000093485 (Ensembl) ENSMUST00000095806 (Ensembl)
rat	Map3k5	RGD:1306565 (Rat Genome Database) 365057 (Entrez Gene) Map3k5 (Alliance of Genome Resources)	Chr1 p12			NP_001264623 (RefSeq) NM_001277694 (RefSeq)
zebrafish	map3k5	ZDB-GENE-030827-3 (Zebrafish Model Organism Database) 555703 (Entrez Gene) map3k5 (Alliance of Genome Resources)	Chr20			NP_001155222 (RefSeq) NM_001161750 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

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