Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KMT2C	HGNC:13726 (HGNC) 58508 (Entrez Gene) 606833 (OMIM) KMT2C (Alliance of Genome Resources)	Chr7 q36.1	Chr7:152134922-152436644 (-) GRCh38	adenoid cystic carcinoma esophagus squamous cell carcinoma Klatskin's tumor Kleefstra syndrome 2 lung adenocarcinoma lung non-small cell carcinoma squamous cell carcinoma stomach cancer	Q8NEZ4 (UniProt | EBI) NM_021230 (RefSeq)
mouse	Kmt2c	MGI:2444959 (MGI) 231051 (Entrez Gene) Gene Tree Kmt2c (Alliance of Genome Resources)	Chr5 12.35 cM	Chr5:25476796-25703781 (-) GRCm39		ENSMUSG00000038056 (Ensembl Gene Model) ENSMUSP00000043874 (Ensembl) ENSMUST00000045291 (Ensembl)
rat	Kmt2c	RGD:1587205 (Rat Genome Database) 502710 (Entrez Gene) Kmt2c (Alliance of Genome Resources)	Chr4 q11			XP_063142868 (RefSeq)
zebrafish	kmt2ca	ZDB-GENE-080520-3 (Zebrafish Model Organism Database) 560793 (Entrez Gene) kmt2ca (Alliance of Genome Resources)	Chr24			XP_005162605 (RefSeq)
	kmt2cb	ZDB-GENE-070705-340 (Zebrafish Model Organism Database) 568162 (Entrez Gene) kmt2cb (Alliance of Genome Resources)	Chr2			XP_009296389 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.