Vertebrate Homology

• Source: Alliance of Genome Resources

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Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TMEM116	HGNC:25084 (HGNC) 89894 (Entrez Gene) TMEM116 (Alliance of Genome Resources)	Chr12 q24.13	Chr12:111931282-112013866 (-) GRCh38		Q8NCL8 (UniProt | EBI) NM_001193453 (RefSeq)
mouse	Tmem116	MGI:1924712 (MGI) 77462 (Entrez Gene) Gene Tree Tmem116 (Alliance of Genome Resources)	Chr5 61.81 cM	Chr5:121590643-121656601 (+) GRCm39		77462 (NCBI Gene Model) NP_001155099 (RefSeq) NM_001161627 (RefSeq)
rat	Tmem116	RGD:1596066 (Rat Genome Database) 690442 (Entrez Gene) Tmem116 (Alliance of Genome Resources)	Chr12 q16			NP_001153097 (RefSeq) NM_001159625 (RefSeq)
zebrafish	tmem116	ZDB-GENE-060526-53 (Zebrafish Model Organism Database) 100003849 (Entrez Gene) tmem116 (Alliance of Genome Resources)	Chr5			A2BGS3 (UniProt | EBI) NM_001114707 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

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