Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	IQSEC1	HGNC:29112 (HGNC) 9922 (Entrez Gene) 610166 (OMIM) IQSEC1 (Alliance of Genome Resources)	Chr3 p25.2-p25.1	Chr3:12897043-13283281 (-) GRCh38	intellectual developmental disorder with short stature and behavioral abnormalities lung adenocarcinoma	Q6DN90 (UniProt | EBI) NM_001330619 (RefSeq)
mouse	Iqsec1	MGI:1196356 (MGI) 232227 (Entrez Gene) Gene Tree Iqsec1 (Alliance of Genome Resources)	Chr6 40.16 cM	Chr6:90636578-90965766 (-) GRCm39		232227 (NCBI Gene Model) Q8R0S2 (UniProt | EBI) NM_001408946 (RefSeq)
rat	Iqsec1	RGD:1596313 (Rat Genome Database) 686590 (Entrez Gene) Iqsec1 (Alliance of Genome Resources)	Chr4			A0A0G2JUG7 (UniProt | EBI) NM_001408960 (RefSeq)
zebrafish	iqsec1a	ZDB-GENE-120813-2 (Zebrafish Model Organism Database) 100334106 (Entrez Gene) iqsec1a (Alliance of Genome Resources)	Chr23			NP_001373528 (RefSeq) NM_001386597 (RefSeq)
	iqsec1b	ZDB-GENE-120813-1 (Zebrafish Model Organism Database) 100148736 (Entrez Gene) iqsec1b (Alliance of Genome Resources)	Chr11			XP_005169389 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.