Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	U2AF2	HGNC:23156 (HGNC) 11338 (Entrez Gene) 191318 (OMIM) U2AF2 (Alliance of Genome Resources)	Chr19 q13.42	Chr19:55654146-55674716 (+) GRCh38	developmental delay, dysmorphic facies, and brain anomalies	P26368 (UniProt | EBI) NM_001012478 (RefSeq)
mouse	U2af2	MGI:98886 (MGI) 22185 (Entrez Gene) Gene Tree U2af2 (Alliance of Genome Resources)	Chr7 2.93 cM	Chr7:5065142-5082937 (+) GRCm39		ENSMUSG00000030435 (Ensembl Gene Model) ENSMUSP00000147013 (Ensembl) ENSMUST00000209099 (Ensembl)
rat	U2af2	RGD:1310690 (Rat Genome Database) 308335 (Entrez Gene) U2af2 (Alliance of Genome Resources)	Chr1 q12			NP_001414127 (RefSeq) NM_001427197 (RefSeq)
zebrafish	u2af2a	ZDB-GENE-050706-131 (Zebrafish Model Organism Database) 557103 (Entrez Gene) u2af2a (Alliance of Genome Resources)	Chr16			NP_001025127 (RefSeq) NM_001029956 (RefSeq)
	u2af2b	ZDB-GENE-040426-1881 (Zebrafish Model Organism Database) 402989 (Entrez Gene) u2af2b (Alliance of Genome Resources)	Chr19			NP_991252 (RefSeq) NM_205689 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.