Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	AGO4	HGNC:18424 (HGNC) 192670 (Entrez Gene) 607356 (OMIM) AGO4 (Alliance of Genome Resources)	Chr1 p34.3	Chr1:35807636-35857890 (+) GRCh38		Q9HCK5 (UniProt | EBI) NM_017629 (RefSeq)
mouse	Ago4	MGI:1924100 (MGI) 76850 (Entrez Gene) Gene Tree Ago4 (Alliance of Genome Resources)	Chr4 60.9 cM	Chr4:126383334-126427265 (-) GRCm39		ENSMUSG00000042500 (Ensembl Gene Model) ENSMUSP00000081312 (Ensembl) ENSMUST00000084289 (Ensembl)
rat	Ago4	RGD:1304583 (Rat Genome Database) 298533 (Entrez Gene) Ago4 (Alliance of Genome Resources)	Chr5 q36			NP_001381300 (RefSeq) NM_001394371 (RefSeq)
zebrafish	ago4	ZDB-GENE-030131-5357 (Zebrafish Model Organism Database) 100535764 (Entrez Gene) ago4 (Alliance of Genome Resources)	Chr19			NP_001239488 (RefSeq) NM_001252559 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

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