Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	ROCK2	HGNC:10252 (HGNC) 9475 (Entrez Gene) 604002 (OMIM) ROCK2 (Alliance of Genome Resources)	Chr2 p25.1	Chr2:11179759-11348330 (-) GRCh38		O75116 (UniProt | EBI) NM_004850 (RefSeq)
mouse	Rock2	MGI:107926 (MGI) 19878 (Entrez Gene) Gene Tree Rock2 (Alliance of Genome Resources)	Chr12 8.04 cM	Chr12:16944896-17037824 (+) GRCm39		ENSMUSG00000020580 (Ensembl Gene Model) ENSMUSP00000152813 (Ensembl) ENSMUST00000220688 (Ensembl)
rat	Rock2	RGD:3590 (Rat Genome Database) 25537 (Entrez Gene) Rock2 (Alliance of Genome Resources)	Chr6 q16			Q62868 (UniProt | EBI) NM_013022 (RefSeq)
zebrafish	rock2a	ZDB-GENE-030115-3 (Zebrafish Model Organism Database) 317747 (Entrez Gene) rock2a (Alliance of Genome Resources)	Chr13			NP_777288 (RefSeq) NM_174863 (RefSeq)
	rock2b	ZDB-GENE-060125-2 (Zebrafish Model Organism Database) 321070 (Entrez Gene) rock2b (Alliance of Genome Resources)	Chr20			NP_001087216 (RefSeq) NM_001093747 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.