Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	KLHL10	HGNC:18829 (HGNC) 317719 (Entrez Gene) 608778 (OMIM) KLHL10 (Alliance of Genome Resources)	Chr17 q21.2	Chr17:41835685-41848384 (+) GRCh38	spermatogenic failure 11	Q6JEL2 (UniProt | EBI) NM_001329595 (RefSeq)
mouse	Klhl10	MGI:2181067 (MGI) 66720 (Entrez Gene) Gene Tree Klhl10 (Alliance of Genome Resources)	Chr11 63.47 cM	Chr11:100332743-100347848 (+) GRCm39		ENSMUSG00000001558 (Ensembl Gene Model) ENSMUSP00000001599 (Ensembl) ENSMUST00000001599 (Ensembl)
rat	Klhl10	RGD:1303290 (Rat Genome Database) 303533 (Entrez Gene) Klhl10 (Alliance of Genome Resources)	Chr10 q31			Q6JEL3 (UniProt | EBI) NM_001001510 (RefSeq)
zebrafish	klhl10a	ZDB-GENE-131015-1 (Zebrafish Model Organism Database) 100333629 (Entrez Gene) klhl10a (Alliance of Genome Resources)	Chr17			XP_017207208 (RefSeq)
	klhl10b.1	ZDB-GENE-131015-2 (Zebrafish Model Organism Database) 560378 (Entrez Gene) klhl10b.1 (Alliance of Genome Resources)	Chr17			XP_021322964 (RefSeq)
	klhl10b.2	ZDB-GENE-131127-61 (Zebrafish Model Organism Database) 560458 (Entrez Gene) klhl10b.2 (Alliance of Genome Resources)	Chr17			XP_021323218 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.