Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	TMCO1	HGNC:18188 (HGNC) 54499 (Entrez Gene) 614123 (OMIM) TMCO1 (Alliance of Genome Resources)	Chr1 q24.1	Chr1:165724291-165827755 (-) GRCh38	craniofacial dysmorphism, skeletal anomalies, and impaired intellectual development syndrome 1	Q9UM00 (UniProt | EBI) NM_001256164 (RefSeq)
mouse	Tmco1	MGI:1921173 (MGI) 68944 (Entrez Gene) Gene Tree Tmco1 (Alliance of Genome Resources)	Chr1 74.69 cM	Chr1:167136239-167161547 (+) GRCm39	craniofacial dysmorphism, skeletal anomalies, and mental retardation syndrome	68944 (NCBI Gene Model) Q921L3 (UniProt | EBI) NM_001039483 (RefSeq)
rat	Tmco1	RGD:1359178 (Rat Genome Database) 289196 (Entrez Gene) Tmco1 (Alliance of Genome Resources)	Chr13 q24			Q5I0H4 (UniProt | EBI) NM_001009631 (RefSeq)
zebrafish	tmco1	ZDB-GENE-050417-344 (Zebrafish Model Organism Database) 378980 (Entrez Gene) tmco1 (Alliance of Genome Resources)	Chr8			NP_001002575 (RefSeq) NM_001002575 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.