Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	E2F3	HGNC:3115 (HGNC) 1871 (Entrez Gene) 600427 (OMIM) E2F3 (Alliance of Genome Resources)	Chr6 p22.3	Chr6:20401879-20493714 (+) GRCh38	lung non-small cell carcinoma	O00716 (UniProt | EBI) NM_001949 (RefSeq)
mouse	E2f3	MGI:1096340 (MGI) 13557 (Entrez Gene) Gene Tree E2f3 (Alliance of Genome Resources)	Chr13 13.09 cM	Chr13:30090558-30170046 (-) GRCm39		ENSMUSG00000016477 (Ensembl Gene Model) ENSMUSP00000100012 (Ensembl) ENSMUST00000102948 (Ensembl)
rat	E2f3	RGD:1561600 (Rat Genome Database) 291105 (Entrez Gene) E2f3 (Alliance of Genome Resources)	Chr17 p12			NP_001131098 (RefSeq) NM_001137626 (RefSeq)
zebrafish	e2f3	ZDB-GENE-070112-882 (Zebrafish Model Organism Database) 791146 (Entrez Gene) e2f3 (Alliance of Genome Resources)	Chr19			NP_001074097 (RefSeq) NM_001080628 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

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