Vertebrate Homology

• Source: Alliance of Genome Resources

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Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	PMPCA	HGNC:18667 (HGNC) 23203 (Entrez Gene) 613036 (OMIM) PMPCA (Alliance of Genome Resources)	Chr9 q34.3	Chr9:136410630-136427992 (+) GRCh38	autosomal recessive spinocerebellar ataxia 2	Q10713 (UniProt | EBI) NM_001282946 (RefSeq)
mouse	Pmpca	MGI:1918568 (MGI) 66865 (Entrez Gene) Gene Tree Pmpca (Alliance of Genome Resources)	Chr2 18.88 cM	Chr2:26279351-26287134 (+) GRCm39		ENSMUSG00000026926 (Ensembl Gene Model) ENSMUSP00000075762 (Ensembl) ENSMUST00000076431 (Ensembl)
rat	Pmpca	RGD:727897 (Rat Genome Database) 296588 (Entrez Gene) Pmpca (Alliance of Genome Resources)	Chr3 p13			P20069 (UniProt | EBI) NM_001003673 (RefSeq)
zebrafish	pmpca	ZDB-GENE-030131-5809 (Zebrafish Model Organism Database) 492801 (Entrez Gene) pmpca (Alliance of Genome Resources)	Chr5			NP_001007443 (RefSeq) NM_001007442 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

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