Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	INSIG2	HGNC:20452 (HGNC) 51141 (Entrez Gene) 608660 (OMIM) INSIG2 (Alliance of Genome Resources)	Chr2 q14.1-q14.2	Chr2:118088452-118110997 (+) GRCh38		Q9Y5U4 (UniProt | EBI) NM_001321331 (RefSeq)
mouse	Insig2	MGI:1920249 (MGI) 72999 (Entrez Gene) Gene Tree Insig2 (Alliance of Genome Resources)	Chr1 52.91 cM	Chr1:121232082-121260318 (-) GRCm39		ENSMUSG00000003721 (Ensembl Gene Model) ENSMUSP00000003818 (Ensembl) ENSMUST00000003818 (Ensembl)
rat	Insig2	RGD:631417 (Rat Genome Database) 288985 (Entrez Gene) Insig2 (Alliance of Genome Resources)	Chr13 q11			Q80UA9 (UniProt | EBI) NM_001431262 (RefSeq)
zebrafish	insig2	ZDB-GENE-040202-1 (Zebrafish Model Organism Database) 399645 (Entrez Gene) insig2 (Alliance of Genome Resources)	Chr9			NP_997969 (RefSeq) NM_212804 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.

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