Vertebrate Homology

• Source: Alliance of Genome Resources

Multiple Genome Viewer

Comparative GO Graph (mouse, human, rat, zebrafish)  

Alliance Homology Information

Species	Symbol	Gene Links	Genetic Location	Genome Coordinates (mouse and human only)	Associated Human Diseases	Sequences
human	CHCHD10	HGNC:15559 (HGNC) 400916 (Entrez Gene) 615903 (OMIM) CHCHD10 (Alliance of Genome Resources)	Chr22 q11.23	Chr22:23765834-23767972 (-) GRCh38	frontotemporal dementia and/or amyotrophic lateral sclerosis 2 isolated mitochondrial myopathy spinal muscular atrophy, Jokela type	Q8WYQ3 (UniProt | EBI) NM_001301339 (RefSeq)
mouse	Chchd10	MGI:2143558 (MGI) 103172 (Entrez Gene) Gene Tree Chchd10 (Alliance of Genome Resources)	Chr10 38.62 cM	Chr10:75768964-75773581 (+) GRCm39	isolated mitochondrial myopathy	ENSMUSG00000049422 (Ensembl Gene Model) ENSMUSP00000059575 (Ensembl) ENSMUST00000058906 (Ensembl)
rat	Chchd10	RGD:1359417 (Rat Genome Database) 361824 (Entrez Gene) Chchd10 (Alliance of Genome Resources)	Chr20 p12			NP_001007009 (RefSeq) NM_001007008 (RefSeq)
zebrafish	chchd10	ZDB-GENE-040426-1753 (Zebrafish Model Organism Database) 393757 (Entrez Gene) chchd10 (Alliance of Genome Resources)	Chr21			NP_957078 (RefSeq) NM_200784 (RefSeq)

Alliance Homology Information

MGI loads orthology data based on the 'stringent' set from the Alliance of Genome Resources. The Alliance sets are based on a scoring system developed by the Alliance in collaboration with DIOPT.

MGI includes orthology for the following vertebrate species from the Alliance:
 - human
 - mouse
 - rat
 - zebrafish

These are a subset of the total species represented in the Alliance; there may be stringent set orthologs in other Alliance species.