Phenotype Image Detail

Image

Caption

Tyrp1^B-lt/Tyrp1^B-lt are distinguished from normal by 2 weeks of age. The hair tips are brown, the rest of the hair shaft is white, often creating a mosaic coat color pattern. Base of hairs become lighter as more pigment is lost with age, older mice are a pale gray in color. Pigment loss is due to premature melanocyte death mediated by natural toxicity of pigment production.

Copyright

Photo donated for Mouse Genome Informatics database use. J:110244

Associated Alleles

Symbol	Name
Tyrp1^B-lt	tyrosinase-related protein 1; light

Associated Genotypes

Allelic Composition	Genetic Background
Tyrp1^B-lt/Tyrp1^B-lt	LT/SvEiJ