Phenotype Image Detail

Image

Caption

Mice homozygous for this autosomal recessive mutation (Ass1^fold/Ass1^fold) have a smaller body size then that of the littermate controls, have a lack of visible hair at one week of age, wrinkled skin by two weeks of age and a sparse looking coat by three weeks of age. Fold/Fold mice have a short lifespan dying at about three weeks of age. Shown here is a one week old Ass1^fold/Ass1^fold mouse on the right with littermate control on the left.

Copyright

Photo courtesy of Mouse Mutant Resource at THe Jackson Laboratory. https://www.jax.org/research-and-faculty/tools/mouse-mutant-resource J:110244

Associated Alleles

Symbol	Name
Ass1^fold	argininosuccinate synthetase 1; follicular dystrophy

Associated Genotypes

Allelic Composition	Genetic Background
Ass1^fold/Ass1^fold	B6Ei.P-Ass1^fold/GrsrJ