Phenotype Image Detail

Image

Caption

Panels A and C represent skin tumor-free mice after chronic treatment. Solid bar represents exposure period for all animals, dotted bar represents exposure period for tumor-free only. Panels B and D represent tumor numbers per mouse after chronic treatment. Solid bar represents exposure period for all animals and dotted bar represents exposure period for tumor-free only. Panel E is a typical example of squamous cell carcinoma found in Ddb2tm1Linn/Ddb2tm1Linn mice, squamous and inflammatory cells are present (arrow). Panel F indicates mitotic figures. Panel G is a typicall example of pappilloma

Copyright

This image is from Itoh T, Proc Natl Acad Sci U S A 2004 Feb 17;101(7):2052-7. Copyright 2004 National Academy of Sciences, U.S.A. J:88125

Associated Alleles

Symbol	Name
Ddb2^tm1Linn	damage specific DNA binding protein 2; targeted mutation 1, Stuart Linn

Associated Genotypes

Allelic Composition	Genetic Background
Ddb2^tm1Linn/Ddb2^tm1Linn	involves: 129S/SvEv * C57BL/6
Ddb2^tm1Linn/Ddb2^+	involves: 129S/SvEv * C57BL/6