Phenotype Image Detail

Image

Caption

Fig 3A. Alizarin red S/alcian blue staining image of trunk in 10.5 day control (upper) and Npr3^stri/Npr3^stri(lower) embryos. Dorsal view from lumbar and sacral regions. All truncal vertebrae are present in mutant mice but are enlarged and transverse process abnormalities vary depending on the vertebrae topograpic position(arrows). Fig 3B. Hematoxylin and eosin-stained histological sections of cervical-thoracic vertebrae in 21 day old control (upper) and Npr3^stri/Npr3^stri(lower) mice. Nucleus pulposus were either absent or smaller in the ventral part of the intervertebral disc in the Npr3^stri/Npr3^stri mice (arrows). Fig 3C. Growth plates show normal thickness but aberrant proliferations at the ventral and dorsal extremities of the Npr3^stri/Npr3^stri mouse (arrowheads). Magnification: 3b: x2; 3c: X40

Copyright

This image is from Jaubert J, Proc Natl Acad Sci U S A 1999 Aug 31;96(18):10278-83. Copyright 1999 National Academy of Sciences, U.S.A. J:57460

Associated Alleles

Symbol	Name
Npr3^stri	natriuretic peptide receptor 3; strigosus

Associated Genotypes

Allelic Composition	Genetic Background
Npr3^stri/Npr3^stri	involves: 129/Sv * FVB/N