Phenotype Image Detail

Image

Caption

Anatomy and histology of mouse kidneys. B) Left kidney of an Aqp2^F204V/Aqp2^F204V mutant mouse (right) compared to a kidney from an age-sex matched unaffected littermate (left). C) Hematoxylin and eosin stained section of ureter from a mutant mouse, showing normal histology despite bloating of the kidney. D) Hematoxylin and eosin stained histologic section of a kidney from a 4-week-old female mutant mouse. The mutant kidney shows marked dilatation of the renal pelvis with blunting of the papilla. There is preservation of the cortex and medulla.

Copyright

This image is from Lloyd DJ, PLoS Genet 2005 Aug 19;1(2):e20, and is displayed under the terms of the Creative Commons Attribution 4.0 International License. J:105809

Associated Alleles

Symbol	Name
Aqp2^F204V	aquaporin 2; Phe204Val

Associated Genotypes

Allelic Composition	Genetic Background
Aqp2^F204V/Aqp2^F204V	C57BL/6-Aqp2^F204V