Phenotype Image Detail

Image

Caption

Panel A. Pathology of the cervical (Panel A), thoracic (Panel B), lumber (Panel C) and sacral (Panel D) spinal cord of an 82-day old Tg(SOD1-G93A)1Gur/0 mouse. More neurofilament (NF) spheroids are seen in the cervical and thoracic spinal cord than in the lumbar and sacral spinal cord (arrowheads). Sections are stained for NFs either with anti-NFL polyclonal antiserum (A and D) or RMO24 mAb (B and C) and counterstained with hematoxylin. Arrows indicate the presence of vacuoles. Scalebar 200um

Copyright

This image is from Tu PH, Proc Natl Acad Sci U S A 1996 Apr 2;93(7):3155-60. Copyright 1996 National Academy of Sciences, U.S.A. J:76718

Associated Alleles

Symbol	Name
Tg(SOD1*G93A)1Gur	transgene insertion 1, Mark E Gurney

Associated Genotypes

Allelic Composition	Genetic Background
Tg(SOD1*G93A)1Gur/0	involves: C57BL/6 * SJL