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Phenotype Image Detail
Image
Caption Electron microscopy analysis indicates structural abnormalities of germ cells. The nucleus is drastically deformed in some cells (B *). Vacuoles are seen inside the nucleus (A,B & E indicated by arrows). Acrosomal malformation with elongated projection is observed (C *). Sperm cells also have detached acrosome (B, C, D arrowheads). The cross-section (E) shows the bent tail next to the nucleus. +/+ wild-type sperm (F) showing normal acrosome and nuclear shape. Scalebar: 0.5um
Copyright This image is from Kotaja N, Proc Natl Acad Sci U S A 2004 Jul 20;101(29):10620-5. Copyright 2004 National Academy of Sciences, U.S.A. J:91483
Associated
Alleles
Symbol Name
Fhl5tm1Saco four and a half LIM domains 5; targeted mutation 1, Paolo Sassone-Corsi
Associated
Genotypes
Allelic Composition Genetic Background
Fhl5tm1Saco/Fhl5tm1Saco involves: 129S2/SvPas * C57BL/6
Contributing Projects:
Mouse Genome Database (MGD), Gene Expression Database (GXD), Mouse Models of Human Cancer database (MMHCdb) (formerly Mouse Tumor Biology (MTB)), Gene Ontology (GO)
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Send questions and comments to User Support. 		last database update
11/12/2024
MGI 6.24 		The Jackson Laboratory