Phenotype Image Detail

Image

Caption

Gross phenotype of Tg(K5-Ptgs2)675Kmd/0, Tg(K5-Ptgs2)19Kmd/0, or Tg(K5-Ptgs2)667Kmd/0 and wild-type mice. A & B: Hind feet of a 7 week old wild-type and transgenic mouse showing the exceptional nail growth of the transegenic. C: By 8 days of age the transegenic mouse remains hairless. D - F: 12 week old wild-type (D) and transgenic (E & F) mice. The transgenic mouse develops a furry coat, however it remains less dense and has a greasy appearance. More severely affected transgenic mice, as shown in E, have much less hair especially in the back skin.

Copyright

This image is from Neufang G, Proc Natl Acad Sci U S A 2001 Jun 19;98(13):7629-34. Copyright 2001 National Academy of Sciences, U.S.A. J:70039

Associated Alleles

Symbol	Name
Tg(K5-Ptgs2)19Kmd	transgene insertion 19, Karin Muller-Decker
Tg(K5-Ptgs2)667Kmd	transgene insertion 667, Karin Muller-Decker
Tg(K5-Ptgs2)675Kmd	transgene insertion 675, Karin Muller-Decker

Associated Genotypes

Allelic Composition	Genetic Background
Tg(K5-Ptgs2)19Kmd/0	involves: NMRI
Tg(K5-Ptgs2)667Kmd/0	involves: NMRI
Tg(K5-Ptgs2)675Kmd/0	involves: NMRI