Phenotype Image Detail

Image

Caption

Membrane-bound storage vacuoles appear electron lucent partly with condensed electron dense structures in electron micrographs of 8 month old Arsb^tm1Cptr/Arsb^tm1Cptr mice. A: Interstitial cell in myocard with large and smaller storage vacuoles. B: Tissue macrophage in the lung with multiple storage vacuoles. C: Liver sinusoid with storage vacuoles in sinus lining endothelial cells. D: Bowman's capsule with storage vacuoles in parietal epithelial cells. Abbreviations: intestinal cells (I); myocard cells (M); capillary lumen (C); aveolar lumen (L); endothelial cells (E); hepatocyte (H); parietal epithelial cells (pE) basal membrane of Bowman's capsule (BM) podocyte (P) Scalebar: 2um

Copyright

This image is from Evers M, Proc Natl Acad Sci U S A 1996 Aug 6;93(16):8214-9. Copyright 1996 National Academy of Sciences, U.S.A. J:34831

Associated Alleles

Symbol	Name
Arsb^tm1Cptr	arylsulfatase B; targeted mutation 1, Christoph Peters

Associated Genotypes

Allelic Composition	Genetic Background
Arsb^tm1Cptr/Arsb^tm1Cptr	involves: 129P2/OlaHsd * C57BL/6J