Phenotype Image Detail

Image

Caption

A: Yolk sacs from E9.5 wild-type and Tal1^tm1Wehi/Tal1^tm1Wehi mice. B & C: E9.5 wild-type and Tal1^tm1Wehi/Tal1^tm1Wehi embryos. D & G: Section through the decidua of E9.0 wild-type and Tal1^tm1Wehi/Tal1^tm1Wehi embryos showing flattening of the yolk sac endoderm and absence of blood islands (arrows) in the Tal1^tm1Wehi/Tal1^tm1Wehi. F & I: Caudal transverse section through wild-type and Tal1^tm1Wehi/Tal1^tm1Wehi. Blood is present in the dorsal aortae (arrows) of the wild-type, but absent from the Tal1^tm1Wehi/Tal1^tm1Wehi embryo. The space between the somites and neural tube is artefactual. Magnification: A: X10; B & C: X25; D & G: X90; E & H: X180 I: X27

Copyright

This image is from Robb L, Proc Natl Acad Sci U S A 1995 Jul 18;92(15):7075-9. Copyright 1995 National Academy of Sciences, U.S.A. J:27458

Associated Alleles

Symbol	Name
Tal1^tm1Wehi	T cell acute lymphocytic leukemia 1; targeted mutation 1, Walter and Eliza Hall Institute of Medical Research

Associated Genotypes

Allelic Composition	Genetic Background
Tal1^tm1Wehi/Tal1^tm1Wehi	involves: 129S1/Sv * C57BL/6