Phenotype Image Detail

Image

Caption

A: 10 week old Tg(Il1a)1.1Tsk/0 mouse (lower) with littermate control (upper). B: Scalp of Tg(Il1a)1.1Tsk/0 mouse showing inflammatory lesion. Noteable is the scaling, etythema and hair loss associated with the lesion. C: Scaling and erythema of the chest. D: 11 month old Tg(Il1a)1.1Tsk/0 mouse displays marked alopecia, weight loss and wrinkling of the skin.

Copyright

This image is from Groves RW, Proc Natl Acad Sci U S A 1995 Dec 5;92(25):11874-8. Copyright 1995 National Academy of Sciences, U.S.A. J:30162

Associated Alleles

Symbol	Name
Tg(Il1a)1.1Tsk	transgene insertion 1.1, Thomas Kupper

Associated Genotypes

Allelic Composition	Genetic Background
Tg(Il1a)1.1Tsk/0	involves: FVB/N