Phenotype Image Detail

Image

Caption

A: Hematoxylin and eosin staining of a testes section from a wild-type mouse. Flagella are apparent in the lumen of the tubule. B: Hematoxylin and eosin staining of a testes section from a Bbs4^tm1Vcs/Bbs4^tm1Vcs mouse showing the absence of flagella in the lumen. C: Toluidine blue staining of a 1um testes section from a wild-type mouse showing spermatozoa with normal morphology as evidenced by the presence of flagella and condensed sperm nuclei. D: Toluidine blue staining of a 1um testes section from a homozygous mutant mouse showing the presence of condensed sperm nuclei in the absence of flagella.

Copyright

This image is from Mykytyn K, Proc Natl Acad Sci U S A 2004 Jun 8;101(23):8664-9. Copyright 2004 National Academy of Sciences, U.S.A. J:90812

Associated Alleles

Symbol	Name
Bbs4^tm1Vcs	Bardet-Biedl syndrome 4; targeted mutation 1, Val C Sheffield

Associated Genotypes

Allelic Composition	Genetic Background
Bbs4^tm1Vcs/Bbs4^tm1Vcs	involves: 129S1/Sv * 129X1/SvJ * C57BL/6J