Phenotype Image Detail

Image

Caption

A: Phenotypes of wild-type and Ggt1^tm1Zuk/Ggt1^tm1Zuk male mice at 14 weeks of age. Wild-type (agouti) mouse (left), Ggt1^tm1Zuk/Ggt1^tm1Zuk mouse (center) and a Ggt1^tm1Zuk/Ggt1^tm1Zuk mouse (right) supplemented with NAC (N-acetylcysteine) in the drinking water from 3 to 14 weeks. B: Eyes from wild-type (left), homozygous mutant mice (center) and NAC supplemented homozygous mutant mice (right) stained with hematoxylin and eosin. Note nuclear and anterior subcapsular epithelial cataracts in eye from an untreated homozygous mutant mouse. Abbreviations: nuclear (N); subcapsular epithelial (S) Magnification: B: x10

Copyright

This image is from Lieberman MW, Proc Natl Acad Sci U S A 1996 Jul 23;93(15):7923-6. Copyright 1996 National Academy of Sciences, U.S.A. J:34309

Associated Alleles

Symbol	Name
Ggt1^tm1Zuk	gamma-glutamyltransferase 1; targeted mutation 1, Martin M Matzuk

Associated Genotypes

Allelic Composition	Genetic Background
Ggt1^tm1Zuk/Ggt1^tm1Zuk	involves: 129S7/SvEvBrd * C57BL/6J