Phenotype Image Detail

Image

Caption

Histological analysis of liver sections from wild-type (A) and Ins1^tm1Jja/Ins1^tm1Jja Ins2^tm1Jja/Ins2^tm1Jja (B). Immunocytochemical staining of pancreas sections of wild-type (C,E & G) and double homozygous mutant mice (D,F & H) with antibodies agains C-peptide1 (C & D), C-peptide 2 (E & F) and glucagon (G & H). lacZ expression in pancreatic section of double homozygous mutant mice visualized by X-Gal staining (J) and background staining obtained with sections from wild-type mice (I) are shown. Scalebar: A & B: 10um; C-J: 8um

Copyright

This image is from Duvillie B, Proc Natl Acad Sci U S A 1997 May 13;94(10):5137-40. Copyright 1997 National Academy of Sciences, U.S.A. J:40377

Associated Alleles

Symbol	Name
Ins1^tm1Jja	insulin I; targeted mutation 1, Jacques Jami
Ins2^tm1Jja	insulin II; targeted mutation 1, Jacques Jami

Associated Genotypes

Allelic Composition	Genetic Background
Ins1^tm1Jja/Ins1^tm1Jja Ins2^tm1Jja/Ins2^tm1Jja	involves: 129S2/SvPas