Phenotype Image Detail

Image

Caption

A & B: Unaffected Slc25a19^tm1Mjl/⁺ control (a) and Slc25a19^tm1Mjl/Slc25a19^tm1Mjl (b) embryos at E10.5 taken at the same magnification. C: Higher magnification of homozygous embryo (b). Note the ruffling along the open neural tube (yellow arrowheads), point of fusion of neural tube (green arrowhead), and lack of color in heart and blood vessels. D: Example of amorphous embryo early in development. Magnification: A & B: x20; C: x50; D: x40

Copyright

This image is from Lindhurst MJ, Proc Natl Acad Sci U S A 2006 Oct 24;103(43):15927-32. Copyright 2006 National Academy of Sciences, U.S.A. J:115337

Associated Alleles

Symbol	Name
Slc25a19^tm1Mjl	solute carrier family 25 (mitochondrial thiamine pyrophosphate carrier), member 19; targeted mutation 1, Marjorie J Lindhurst

Associated Genotypes

Allelic Composition	Genetic Background
Slc25a19^tm1Mjl/Slc25a19^tm1Mjl	either: (involves: 129S6/SvEvTac) or (involves: 129S6/SvEvTac * Black Swiss)