Phenotype Image Detail

Image

Caption

Renal cysts and Pkd1 expression in embryonic and adult kidneys of Pkd1^tm1Rsa/Pkd1⁺ mice demonstrated by using X-Gal staining. Renal cysts (cy) in heterozygous mice were lined with hyperplactic epithelial cells (a, arrowed) or cells with pyknotic apoptotic nuclei (b, x60).

Copyright

This image is from Boulter C, Proc Natl Acad Sci U S A 2001 Oct 9;98(21):12174-9. Copyright 2001 National Academy of Sciences, U.S.A. J:72238

Associated Alleles

Symbol	Name
Pkd1^tm1Rsa	polycystin 1, transient receptor potential channel interacting; targeted mutation 1, Richard Sandford

Associated Genotypes

Allelic Composition	Genetic Background
Pkd1^tm1Rsa/Pkd1^+	involves: 129S4/SvJaeSor