Phenotype Image Detail

Image

Caption

Alizarin red S staining of the skeletons of newborn wild-type, Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju transgenic mice. Lateral view of skull, thoracic cage, and hindlimb; and frontal view of lumbar vertebra of a wild-type mouse (left), and a Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju (right) littermate. Abbreviations: supraoccipital bone (so); sternum (st); lumbar vertebrae (vt); ischium (is); pubic bone (pb); tibia (tb).

Copyright

This image is from Schipani E, Proc Natl Acad Sci U S A 1997 Dec 9;94(25):13689-94. Copyright 1997 National Academy of Sciences, U.S.A. J:77639

Associated Alleles

Symbol	Name
Tg(Col2a1-PTHR1*H223R)AHju	transgene insertion A, Harald Juppner

Associated Genotypes

Allelic Composition	Genetic Background
Tg(Col2a1-PTHR1*H223R)AHju/Tg(Col2a1-PTHR1*H223R)AHju	involves: C57BL/6