Phenotype Image Detail

Image

Caption

Chronic inflammation of the stomach in Aire^tm1.1Doi/Aire^tm1.1Doi mice. H & E-stained paraffin stomach sections with normal gastric anatomy from a 20 week old wild-type mouse (left). Inflammatory infiltrates in the stomach mucosa of an age and sex matched Aire^tm1.1Doi/Aire^tm1.1Doi mouse (right). Magnification x10

Copyright

This image is from Gavanescu I, Proc Natl Acad Sci U S A 2007 Mar 13;104(11):4583-7. Copyright 2007 National Academy of Sciences, U.S.A. J:119475

Associated Alleles

Symbol	Name
Aire^tm1.1Doi	autoimmune regulator; targeted mutation 1.1, Christophe Benoist and Diane Mathis

Associated Genotypes

Allelic Composition	Genetic Background
Aire^tm1.1Doi/Aire^tm1.1Doi	involves: 129S2/SvPas * C57BL/6