Phenotype Image Detail

Image

Caption

Representative photos of transverse sections at indicated levels stained with hematoxylin/eosin. Wild-type vessels (left). Note an increased diameter of the vessel with a thickening of adventitia (a) and thinning of the medial layer (m) in the Fbln5^tm1Eno/Fbln5^tm1Eno vessel. Thrombus formation (thr) and neovascularization (nv) were observed in the homozygote. neointima (ni) Scalebars: 40um

Copyright

This image is from Spencer JA, Proc Natl Acad Sci U S A 2005 Feb 22;102(8):2946-51. Copyright 2005 National Academy of Sciences, U.S.A. J:96831

Associated Alleles

Symbol	Name
Fbln5^tm1Eno	fibulin 5; targeted mutation 1, Eric N Olson

Associated Genotypes

Allelic Composition	Genetic Background
Fbln5^tm1Eno/Fbln5^tm1Eno	involves: 129S6/SvEvTac * C57BL/6