Phenotype Image Detail

Image

Caption

Sections through the knee joint articular cartilage from 9 month old wild-type control and Col9a1^tm1Jae/Col9a1^tm1Jae mice stained with Weigert's iron hematoxylin/Fast green/safranin-O. A & B: Cross sections through the femoral condylar surfaces from wild-type (A) and mutant (B) mice showing the uniform characteristics of the normal articular cartilage as compared to the irregular characteristics of the mutant articular cartilage. C & D: Cross sections through the tibial condylar surfaces of wild-type (C) and mutant (D) mice showing the uniform characteristics of the normal articular cartilage as compared with the irregular characteristics of the mutant articular cartilage; also note the sclerosis of subchondral bone in the mutant. Magnification x50

Copyright

This image is from Fassler R, Proc Natl Acad Sci U S A 1994 May 24;91(11):5070-4. Copyright 1994 National Academy of Sciences, U.S.A. J:18628

Associated Alleles

Symbol	Name
Col9a1^tm1Jae	collagen, type IX, alpha 1; targeted mutation 1, Rudolf Jaenisch

Associated Genotypes

Allelic Composition	Genetic Background
Col9a1^tm1Jae/Col9a1^tm1Jae	either: (involves: 129S2/SvPas * BALB/c) or (involves: 129S2/SvPas * C57BL)